Development of Acid-Resistant Alginate/Trimethyl Chitosan Nanoparticles Containing Cationic β-Cyclodextrin Polymers for Insulin Oral Delivery

In this study, the use of trimethylchitosan (TMC), by higher solubility in comparison with chitosan, in alginate/chitosan nanoparticles containing cationic β-cyclodextrin polymers (CPβCDs) has been studied, with the aim of increasing insulin uptake by nanoparticles. Firstly, TMCs were synthesized by...

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Bibliographische Detailangaben
Veröffentlicht in:AAPS PharmSciTech
Hauptverfasser: Mansourpour, Maryam, Mahjub, Reza, Amini, Mohsen, Ostad, Seyed Naser, Shamsa, Elnaz Sadat, Rafiee- Tehrani, Morteza, Dorkoosh, Farid Abedin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508306/
https://ncbi.nlm.nih.gov/pubmed/25604700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0282-9
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