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Preparation, Statistical Optimization, and In vitro Characterization of Insulin Nanoparticles Composed of Quaternized Aromatic Derivatives of Chitosan
The aim of this study was the preparation, optimization, and in vitro characterization of insulin nanoparticles composed of methylated N-(4-N,N-dimethylaminobenzyl), methylated N-(4-pyridinyl), and methylated N-(benzyl) chitosan. Three types of derivatives were synthesized by the Schiff base reactio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225557/ https://ncbi.nlm.nih.gov/pubmed/22033812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9716-9 |
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