Upregulation of Autophagy Decreases Chlorine Gas Induced Mitochondrial Injury and Lung Inflammation

The mechanisms of toxicity during exposure of the airways to chlorinated biomolecules generated during the course of inflammation and chlorine (Cl(2)) gas are poorly understood. We hypothesized that lung epithelial cell mitochondria are damaged by Cl(2) exposure and activation of autophagy mitigates...

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Gepubliceerd in:Free Radic Biol Med
Hoofdauteurs: Jurkuvenaite, Asta, Benavides, Gloria A., Komarova, Svetlana, Doran, Stephen F., Johnson, Michelle, Aggarwal, Saurabh, Zhang, Jianhua, Darley-Usmar, Victor M., Matalon, Sadis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508227/
https://ncbi.nlm.nih.gov/pubmed/25881550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.03.039
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