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Upregulation of Autophagy Decreases Chlorine Gas Induced Mitochondrial Injury and Lung Inflammation

The mechanisms of toxicity during exposure of the airways to chlorinated biomolecules generated during the course of inflammation and chlorine (Cl(2)) gas are poorly understood. We hypothesized that lung epithelial cell mitochondria are damaged by Cl(2) exposure and activation of autophagy mitigates...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Jurkuvenaite, Asta, Benavides, Gloria A., Komarova, Svetlana, Doran, Stephen F., Johnson, Michelle, Aggarwal, Saurabh, Zhang, Jianhua, Darley-Usmar, Victor M., Matalon, Sadis
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508227/
https://ncbi.nlm.nih.gov/pubmed/25881550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.03.039
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