A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis

Peritoneal carcinomatosis is a major source of morbidity and mortality in patients with advanced abdominal neoplasms. Intraperitoneal chemotherapy (IPC) is an area of intense interest given its efficacy in ovarian cancer. However, IPC suffers from poor drug penetration into peritoneal tumors. As suc...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Sugahara, Kazuki N., Scodeller, Pablo, Braun, Gary B., de Mendoza, Tatiana Hurtado, Yamazaki, Chisato M., Kluger, Michael D., Kitayama, Joji, Alvarez, Edwin, Howell, Stephen B., Teesalu, Tambet, Ruoslahti, Erkki, Lowy, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508207/
https://ncbi.nlm.nih.gov/pubmed/26071630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.06.009
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