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Stress sounds the alarmin: the role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming

High mobility group box-1 (HMGB1) is an endogenous danger signal or alarmin that mediates activation of the innate immune response including chemotaxis and pro-inflammatory cytokine release. HMGB1 has been implicated in the pathophysiology of several neuroinflammatory conditions including ischemia,...

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Veröffentlicht in:Brain Behav Immun
Hauptverfasser: Frank, Matthew G., Weber, Michael D., Watkins, Linda R., Maier, Steven F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508196/
https://ncbi.nlm.nih.gov/pubmed/25816800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.03.010
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