Pro-Inflammatory Cytokines Predict Relapse-Free Survival after One Month of Interferon-α but Not Observation in Intermediate Risk Melanoma Patients

BACKGROUND: E1697 was a phase III trial of adjuvant interferon (IFN)-α2b for one month (Arm B) versus observation (Arm A) in patients with resected melanoma at intermediate risk. We evaluated the levels of candidate serum cytokines, the HLA genotype, polymorphisms of CTLA4 and FOXP3 genes and the de...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tarhini, Ahmad A., Lin, Yan, Zahoor, Haris, Shuai, Yongli, Butterfield, Lisa H., Ringquist, Steven, Gogas, Helen, Sander, Cindy, Lee, Sandra, Agarwala, Sanjiv S., Kirwood, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508028/
https://ncbi.nlm.nih.gov/pubmed/26192408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132745
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