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Clinical and Immunologic Basis of Interferon Therapy in Melanoma

Interferon α2b (IFN-α2b) at high dosage is critical to the reversal of signaling defects in T cells of melanoma patients, and to the durable effector (α DC1) polarization of dendritic cells. These immunoregulatory effects appear to be uniquely achieved with levels of IFN-α only attainable in vivo us...

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Detalles Bibliográficos
Main Authors: Tarhini, Ahmad A., Kirkwood, John M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428067/
https://ncbi.nlm.nih.gov/pubmed/20074274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05073.x
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