Vorinostat: A Potent Agent to Prevent and Treat Laser-induced Corneal Haze

PURPOSE: This study investigated the efficacy and safety of vorinostat, a deacetylase (HDAC) inhibitor, in the treatment of laser-induced corneal haze following photorefractive keratectomy (PRK) in rabbits in vivo and transforming growth factor beta 1 (TGFβ1) -induced corneal fibrosis in vitro. METH...

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Pubblicato in:J Refract Surg
Autori principali: Tandon, Ashish, Tovey, Jonathan C.K., Waggoner, Michael R., Sharma, Ajay, Cowden, John W., Gibson, Daniel J., Liu, Yuanjing, Schultz, Gregory S., Mohan, Rajiv R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508025/
https://ncbi.nlm.nih.gov/pubmed/22386369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3928/1081597X-20120210-01
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