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Trichostatin A Inhibits Corneal Haze In Vitro and In Vivo

PURPOSE: Trichostatin A (TSA), a histone deacetylase inhibitor, has been shown to suppress TGF-β-induced fibrogenesis in many nonocular tissues. The authors evaluated TSA cytotoxicity and its antifibrogenic activity on TGF-β– driven fibrosis in the cornea with the use of in vitro and in vivo models....

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Main Authors: Sharma, Ajay, Mehan, Maneesh M., Sinha, Sunilima, Cowden, John W., Mohan, Rajiv R.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711114/
https://ncbi.nlm.nih.gov/pubmed/19168895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2919
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