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Trichostatin A Inhibits Corneal Haze In Vitro and In Vivo
PURPOSE: Trichostatin A (TSA), a histone deacetylase inhibitor, has been shown to suppress TGF-β-induced fibrogenesis in many nonocular tissues. The authors evaluated TSA cytotoxicity and its antifibrogenic activity on TGF-β– driven fibrosis in the cornea with the use of in vitro and in vivo models....
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711114/ https://ncbi.nlm.nih.gov/pubmed/19168895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2919 |
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