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Effect of Prophylactic and Therapeutic Mitomycin C on Corneal Apoptosis, Cellular Proliferation, Haze, and Long-term Keratocyte Density in Rabbits

PURPOSE: To determine the mechanism through which topical mitomycin C prevents and treats corneal haze after photorefractive keratectomy (PRK) and to examine the effects of dosage and duration of exposure. METHODS: In 224 New Zealand rabbits, −9.0 diopter PRK with mitomycin C or balanced salt soluti...

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Detalhes bibliográficos
Main Authors: Netto, Marcelo V., Mohan, Rajiv R., Sinha, Sunilima, Sharma, Ajay, Gupta, Pankaj C., Wilson, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756017/
https://ncbi.nlm.nih.gov/pubmed/16805119
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