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The Rügheimer-Burrows reaction revisited: Facile preparation of 4-alkylisoquinolines and 3,5-dialkylpyridines from (partially) saturated amines
[Image: see text] A long-known class of cyclic amine/aldehyde condensation reactions was reinvestigated. Benzoic acid was found to efficiently promote condensations of amines such as piperidine or 1,2,3,4-tetrahydroisoquinoline with aromatic aldehydes, resulting in amine β-functionalization and arom...
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| Publicado no: | Tetrahedron Lett |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507826/ https://ncbi.nlm.nih.gov/pubmed/26207074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2014.11.137 |
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