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2-acetylphenol analogs as potent reversible monoamine oxidase inhibitors

Based on a previous report that substituted 2-acetylphenols may be promising leads for the design of novel monoamine oxidase (MAO) inhibitors, a series of C5-substituted 2-acetylphenol analogs (15) and related compounds (two) were synthesized and evaluated as inhibitors of human MAO-A and MAO-B. Gen...

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Publicat a:Drug Des Devel Ther
Autors principals: Legoabe, Lesetja J, Petzer, Anél, Petzer, Jacobus P
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507791/
https://ncbi.nlm.nih.gov/pubmed/26203229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86225
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