Plasma BDNF levels associate with Pittsburgh Compound B binding in the brain

BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays an important role in Alzheimer's disease (AD) and other neurodegenerative disorders. BDNF function is adversely affected by amyloid beta in AD. BDNF levels in brain and peripheral tissues are lower in patients with AD and mild cognitive...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Hwang, Kristy S., Lazaris, Andreas S., Eastman, Jennifer A., Teng, Edmond, Thompson, Paul M., Gylys, Karen H., Cole, Gregory M., Apostolova, Liana G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
Témata:
Blood-Based Biomarkers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507280/
https://ncbi.nlm.nih.gov/pubmed/26207261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2015.01.005
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