Alzheimer risk genes modulate the relationship between plasma apoE and cortical PiB binding

OBJECTIVE: We investigated the association between apoE protein plasma levels and brain amyloidosis and the effect of the top 10 Alzheimer disease (AD) risk genes on this association. METHODS: Our dataset consisted of 18 AD, 52 mild cognitive impairment, and 3 cognitively normal Alzheimer's Dis...

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Detalhes bibliográficos
Publicado no:Neurol Genet
Main Authors: Lazaris, Andreas, Hwang, Kristy S., Goukasian, Naira, Ramirez, Leslie M., Eastman, Jennifer, Blanken, Anna E., Teng, Edmond, Gylys, Karen, Cole, Greg, Saykin, Andrew J., Shaw, Leslie M., Trojanowski, John Q., Jagust, William J., Weiner, Michael W., Apostolova, Liana G.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809461/
https://ncbi.nlm.nih.gov/pubmed/27066559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000022
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