MicroRNA-148a reduces tumorigenesis and increases TRAIL-induced apoptosis in NSCLC

Nonsmall cell lung cancer (NSCLC) is one of the leading causes of death worldwide. TNF-related apoptosis-inducing ligand (TRAIL) has been shown to induce apoptosis in malignant cells without inducing significant toxicity in normal cells. However, several carcinomas, including lung cancer, remain res...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Joshi, Pooja, Jeon, Young-Jun, Laganà, Alessandro, Middleton, Justin, Secchiero, Paola, Garofalo, Michela, Croce, Carlo M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507199/
https://ncbi.nlm.nih.gov/pubmed/26124099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500886112
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