MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer

Lung cancer is the leading cause of cancer mortality in the world today. Although some advances in lung cancer therapy have been made, patient survival is still poor. MicroRNAs (miRNAs) can act as oncogenes or tumor-suppressor genes in human malignancy. The miR-34 family consists of tumor-suppressiv...

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Detalhes bibliográficos
Main Authors: Garofalo, Michela, Jeon, Young-Jun, Nuovo, Gerard J., Middleton, Justin, Secchiero, Paola, Joshi, Pooja, Alder, Hansjuerg, Nazaryan, Natalya, Di Leva, Gianpiero, Romano, Giulia, Crawford, Melissa, Nana-Sinkam, Patrick, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689725/
https://ncbi.nlm.nih.gov/pubmed/23805317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067581
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