MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer

Lung cancer is the leading cause of cancer mortality in the world today. Although some advances in lung cancer therapy have been made, patient survival is still poor. MicroRNAs (miRNAs) can act as oncogenes or tumor-suppressor genes in human malignancy. The miR-34 family consists of tumor-suppressiv...

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Hoofdauteurs: Garofalo, Michela, Jeon, Young-Jun, Nuovo, Gerard J., Middleton, Justin, Secchiero, Paola, Joshi, Pooja, Alder, Hansjuerg, Nazaryan, Natalya, Di Leva, Gianpiero, Romano, Giulia, Crawford, Melissa, Nana-Sinkam, Patrick, Croce, Carlo M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689725/
https://ncbi.nlm.nih.gov/pubmed/23805317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067581
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