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Sulfonoquinovosyl diacylglyceride selectively targets acute lymphoblastic leukemia cells and exerts potent anti-leukemic effects in vivo

DNA topoisomerase II inhibitors e.g. doxorubicin and etoposide are currently used in the chemotherapy for acute lymphoblastic leukemia (ALL). These inhibitors have serious side effects during the chemotherapy e.g. cardiotoxicity and secondary malignancies. In this study we show that sulfonoquinovosy...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Jain, Chetan Kumar, Pradhan, Bhola Shankar, Banerjee, Sukdeb, Mondal, Nirup Bikash, Majumder, Subeer S., Bhattacharyya, Madhumita, Chakrabarti, Saikat, Roychoudhury, Susanta, Majumder, Hemanta Kumar
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507174/
https://ncbi.nlm.nih.gov/pubmed/26189912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12082
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