Sulfonoquinovosyl diacylglyceride selectively targets acute lymphoblastic leukemia cells and exerts potent anti-leukemic effects in vivo

DNA topoisomerase II inhibitors e.g. doxorubicin and etoposide are currently used in the chemotherapy for acute lymphoblastic leukemia (ALL). These inhibitors have serious side effects during the chemotherapy e.g. cardiotoxicity and secondary malignancies. In this study we show that sulfonoquinovosy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jain, Chetan Kumar, Pradhan, Bhola Shankar, Banerjee, Sukdeb, Mondal, Nirup Bikash, Majumder, Subeer S., Bhattacharyya, Madhumita, Chakrabarti, Saikat, Roychoudhury, Susanta, Majumder, Hemanta Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507174/
https://ncbi.nlm.nih.gov/pubmed/26189912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12082
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