Synergistic enhancement of parasiticidal activity of amphotericin B using copaiba oil in nanoemulsified carrier for oral delivery: an approach for non-toxic chemotherapy

BACKGROUND AND PURPOSE: The aim of this study was to devise a nanoemulsified carrier system (CopNEC) to improve the oral delivery of amphotericin B (AmB) by increasing its oral bioavailability and synergistically enhance its antileishmanial activity with copaiba oil (Cop). EXPERIMENTAL APPROACH: The...

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Bibliografski detalji
Izdano u:Br J Pharmacol
Glavni autori: Gupta, Pramod K, Jaiswal, Anil K, Asthana, Shalini, Teja B, Venkatesh, Shukla, Prashant, Shukla, Minakshi, Sagar, Neeti, Dube, Anuradha, Rath, Srikanta K, Mishra, Prabhat R
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Research Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507162/
https://ncbi.nlm.nih.gov/pubmed/25825339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13149
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