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Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites

Histone deacetylase (HDAC) enzymes work together with histone acetyltransferases (HATs) to reversibly acetylate both histone and non-histone proteins. As a result, these enzymes are involved in regulating chromatin structure and gene expression as well as other important cellular processes. HDACs ar...

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Bibliografiske detaljer
Udgivet i:Int J Parasitol Drugs Drug Resist
Main Authors: Engel, Jessica A., Jones, Amy J., Avery, Vicky M., Sumanadasa, Subathdrage D.M., Ng, Susanna S., Fairlie, David P., Adams, Tina S., Andrews, Katherine T.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506969/
https://ncbi.nlm.nih.gov/pubmed/26199860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2015.05.004
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