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Properdin contributes to allergic airway inflammation through local C3a generation()

Complement is implicated in asthma pathogenesis but its mechanism of action in this disease remains incompletely understood. Here we studied the role of properdin (P), a positive alternative pathway complement regulator, in allergen-induced airway inflammation. Allergen challenge stimulated P releas...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wang, Yuan, Miwa, Takashi, Ducka-Kokalari, Blerina, Redai, Imre G., Sato, Sayaka, Gullipalli, Damodar, Zangrilli, James G., Haczku, Angela, Song, Wen-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506880/
https://ncbi.nlm.nih.gov/pubmed/26116506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401819
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