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Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice

Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease. We and others showed that presence of the epithelial-derived surfactant protein-D (SP-D) is important in...

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Main Authors: Cameron H. Flayer, Moyar Q. Ge, Jin W. Hwang, Blerina Kokalari, Imre G. Redai, Zhilong Jiang, Angela Haczku
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-09-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.02173/full
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