SCARB2/LIMP-2 Regulates IFN Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7

Scavenger receptor class B, member 2 (SCARB2) is essential for endosome biogenesis and reorganization and serves as a receptor for both β-glucocerebrosidase and enterovirus 71. However, little is known about its function in innate immune cells. In this study, we show that, among human peripheral blo...

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Gepubliceerd in:J Immunol
Hoofdauteurs: Guo, Hao, Zhang, Jialong, Zhang, Xuyuan, Wang, Yanbing, Yu, Haisheng, Yin, Xiangyun, Li, Jingyun, Du, Peishuang, Plumas, Joel, Chaperot, Laurence, Chen, Jianzhu, Su, Lishan, Liu, Yongjun, Zhang, Liguo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506778/
https://ncbi.nlm.nih.gov/pubmed/25862818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402312
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