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Lack of Major Histocompatibility Complex Class I Upregulation and Restrictive Infection by JC Virus Hampers Detection of Neurons by T-Lymphocytes in the Central Nervous System
The human polyomavirus JC (JCV) infects glial cells in immunosuppressed individuals leading to progressive multifocal leukoencephalopathy (PML). JCV can also infect neurons in patients with JCV granule cell neuronopathy and JCV encephalopathy. CD8-positive T-cells play a crucial role in viral contai...
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| Publicado no: | J Neuropathol Exp Neurol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506730/ https://ncbi.nlm.nih.gov/pubmed/26115192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000218 |
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