Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells

BACKGROUND: The vasculature of the brain is composed of endothelial cells, pericytes and astrocytic processes. The endothelial cells are the critical interface between the blood and the CNS parenchyma and are a critical component of the blood-brain barrier (BBB). These cells are innately programmed...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: O’Carroll, Simon J., Kho, Dan Ting, Wiltshire, Rachael, Nelson, Vicky, Rotimi, Odunayo, Johnson, Rebecca, Angel, Catherine E., Graham, E. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506411/
https://ncbi.nlm.nih.gov/pubmed/26152369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0346-0
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