Tumour-suppressive microRNA-144-5p directly targets CCNE1/2 as potential prognostic markers in bladder cancer

BACKGROUND: Analysis of a microRNA (miRNA) expression signature of bladder cancer (BC) by deep-sequencing revealed that clustered miRNAs microRNA (miR)-451a, miR-144-3p, and miR-144-5p were significantly downregulated in BC tissues. We hypothesised that these miRNAs function as tumour suppressors in...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Matsushita, R, Seki, N, Chiyomaru, T, Inoguchi, S, Ishihara, T, Goto, Y, Nishikawa, R, Mataki, H, Tatarano, S, Itesako, T, Nakagawa, M, Enokida, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506384/
https://ncbi.nlm.nih.gov/pubmed/26057453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.195
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