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HDL-bound sphingosine 1-phosphate restrains lymphopoiesis and neuroinflammation
Lipid mediators influence immunity in myriad ways. For example, circulating sphingosine 1-phosphate (S1P) is a key regulator of lymphocyte egress(1,2). Although the majority of plasma S1P is bound to apolipoprotein M (ApoM) in the high-density lipoprotein (HDL) particle(3), immunological functions o...
Shranjeno v:
| izdano v: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506268/ https://ncbi.nlm.nih.gov/pubmed/26053123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14462 |
| Oznake: |
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