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HDL-bound sphingosine 1-phosphate restrains lymphopoiesis and neuroinflammation
Lipid mediators influence immunity in myriad ways. For example, circulating sphingosine 1-phosphate (S1P) is a key regulator of lymphocyte egress(1,2). Although the majority of plasma S1P is bound to apolipoprotein M (ApoM) in the high-density lipoprotein (HDL) particle(3), immunological functions o...
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| Publicado en: | Nature |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506268/ https://ncbi.nlm.nih.gov/pubmed/26053123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14462 |
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