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Surrogate markers for time-varying treatments and outcomes

BACKGROUND: A surrogate marker is a variable commonly used in clinical trials to guide treatment decisions when the outcome of ultimate interest is not available. A good surrogate marker is one where the treatment effect on the surrogate is a strong predictor of the effect of treatment on the outcom...

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Dettagli Bibliografici
Pubblicato in:Clin Trials
Autori principali: Hsu, Jesse Y, Kennedy, Edward H, Roy, Jason A, Stephens-Shields, Alisa J, Small, Dylan S, Joffe, Marshall M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506229/
https://ncbi.nlm.nih.gov/pubmed/25948621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774515583500
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