Detection, characterization and inhibition of FGFR-TACC fusions in IDH wild type glioma

PURPOSE: Oncogenic fusions consisting of FGFR and TACC are present in a subgroup of glioblastoma (GBM) and other human cancers and have been proposed as new therapeutic targets. We analyzed frequency, molecular features of FGFR-TACC fusions, and explored the therapeutic efficacy of inhibiting FGFR k...

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Опубликовано в: :Clin Cancer Res
Главные авторы: Di Stefano, Anna Luisa, Fucci, Alessandra, Frattini, Veronique, Labussiere, Marianne, Mokhtari, Karima, Zoppoli, Pietro, Marie, Yannick, Bruno, Aurelie, Boisselier, Blandine, Giry, Marine, Savatovsky, Julien, Touat, Mehdi, Belaid, Hayat, Kamoun, Aurelie, Idbaih, Ahmed, Houillier, Caroline, Luo, Feng R., Soria, Jean-Charles, Tabernero, Josep, Eoli, Marica, Paterra, Rosina, Yip, Stephen, Petrecca, Kevin, Chan, Jennifer A., Finocchiaro, Gaetano, Lasorella, Anna, Sanson, Marc, Iavarone, Antonio
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506218/
https://ncbi.nlm.nih.gov/pubmed/25609060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2199
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