Detection, characterization and inhibition of FGFR-TACC fusions in IDH wild type glioma

PURPOSE: Oncogenic fusions consisting of FGFR and TACC are present in a subgroup of glioblastoma (GBM) and other human cancers and have been proposed as new therapeutic targets. We analyzed frequency, molecular features of FGFR-TACC fusions, and explored the therapeutic efficacy of inhibiting FGFR k...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Di Stefano, Anna Luisa, Fucci, Alessandra, Frattini, Veronique, Labussiere, Marianne, Mokhtari, Karima, Zoppoli, Pietro, Marie, Yannick, Bruno, Aurelie, Boisselier, Blandine, Giry, Marine, Savatovsky, Julien, Touat, Mehdi, Belaid, Hayat, Kamoun, Aurelie, Idbaih, Ahmed, Houillier, Caroline, Luo, Feng R., Soria, Jean-Charles, Tabernero, Josep, Eoli, Marica, Paterra, Rosina, Yip, Stephen, Petrecca, Kevin, Chan, Jennifer A., Finocchiaro, Gaetano, Lasorella, Anna, Sanson, Marc, Iavarone, Antonio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506218/
https://ncbi.nlm.nih.gov/pubmed/25609060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2199
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