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Protein kinase C bidirectionally modulates I(h) and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel surface expression in hippocampal pyramidal neurons

KEY POINTS: Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, particularly that of the HCN1 isoform, are enriched in the distal dendrites of hippocampal CA1 pyramidal neurons; these channels have physiological functions with respect to decreasing neuronal excitability. . In the pre...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Williams, Aaron D, Jung, Sangwook, Poolos, Nicholas P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506181/
https://ncbi.nlm.nih.gov/pubmed/25820761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270453
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