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Genital tenofovir concentrations correlate with protection against HIV infection in the CAPRISA 004 trial: Importance of adherence for microbicide effectiveness
OBJECTIVE: The CAPRISA 004 trial showed that coitally-dosed tenofovir 1% gel reduced HIV acquisition by 39% overall and 54% when used consistently. The objective of this analysis was to ascertain its pharmacokinetic-pharmacodynamic relationship to protection against HIV acquisition. DESIGN: Genital...
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| Veröffentlicht in: | J Acquir Immune Defic Syndr |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505741/ https://ncbi.nlm.nih.gov/pubmed/26181703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000607 |
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