Chargement en cours...

Identification of Influenza A Virus PB2 Residues Involved in Enhanced Polymerase Activity and Virus Growth in Mammalian Cells at Low Temperatures

Mutations in the polymerase genes are known to play a major role in avian influenza virus adaptation to mammalian hosts. Despite having avian origin PA and PB2, the 2009 pandemic H1N1 virus (pH1N1) can replicate well in mammalian respiratory tracts, suggesting that these proteins have acquired mutat...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Hayashi, Tsuyoshi, Wills, Saintedym, Bussey, Kendra A., Takimoto, Toru
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505657/
https://ncbi.nlm.nih.gov/pubmed/26018156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00901-15
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!