Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62

Autophagic flux involves formation of autophagosomes and their degradation by lysosomes. Autophagy can either promote or restrict viral replication. In the case of Dengue virus (DENV), several studies report that autophagy supports the viral replication cycle, and describe an increase of autophagic...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Metz, Philippe, Chiramel, Abhilash, Chatel-Chaix, Laurent, Alvisi, Gualtiero, Bankhead, Peter, Mora-Rodríguez, Rodrigo, Long, Gang, Hamacher-Brady, Anne, Brady, Nathan R., Bartenschlager, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505648/
https://ncbi.nlm.nih.gov/pubmed/26018155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00787-15
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