Structural and Biochemical Basis for the Inhibitory Effect of Liprin-α3 on Mouse Diaphanous 1 (mDia1) Function

Diaphanous-related formins are eukaryotic actin nucleation factors regulated by an autoinhibitory interaction between the N-terminal RhoGTPase-binding domain (mDia(N)) and the C-terminal Diaphanous-autoregulatory domain (DAD). Although the activation of formins by Rho proteins is well characterized,...

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Vydáno v:J Biol Chem
Hlavní autoři: Brenig, Julian, de Boor, Susanne, Knyphausen, Philipp, Kuhlmann, Nora, Wroblowski, Sarah, Baldus, Linda, Scislowski, Lukas, Artz, Oliver, Trauschies, Philip, Baumann, Ulrich, Neundorf, Ines, Lammers, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505501/
https://ncbi.nlm.nih.gov/pubmed/25911102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.621946
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