The Function of Embryonic Stem Cell-expressed RAS (E-RAS), a Unique RAS Family Member, Correlates with Its Additional Motifs and Its Structural Properties

E-RAS is a member of the RAS family specifically expressed in embryonic stem cells, gastric tumors, and hepatic stellate cells. Unlike classical RAS isoforms (H-, N-, and K-RAS4B), E-RAS has, in addition to striking and remarkable sequence deviations, an extended 38-amino acid-long unique N-terminal...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nakhaei-Rad, Saeideh, Nakhaeizadeh, Hossein, Kordes, Claus, Cirstea, Ion C., Schmick, Malte, Dvorsky, Radovan, Bastiaens, Philippe I. H., Häussinger, Dieter, Ahmadian, Mohammad Reza
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505495/
https://ncbi.nlm.nih.gov/pubmed/25940089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.640607
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