Deletion of the Tail Domain of the Kinesin-5 Cin8 Affects Its Directionality

The bipolar kinesin-5 motors are one of the major players that govern mitotic spindle dynamics. Their bipolar structure enables them to cross-link and slide apart antiparallel microtubules (MTs) emanating from the opposing spindle poles. The budding yeast kinesin-5 Cin8 was shown to switch from fast...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Düselder, André, Fridman, Vladimir, Thiede, Christina, Wiesbaum, Alice, Goldstein, Alina, Klopfenstein, Dieter R., Zaitseva, Olga, Janson, Marcel E., Gheber, Larisa, Schmidt, Christoph F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Molecular Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505430/
https://ncbi.nlm.nih.gov/pubmed/25991727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.620799
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