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A potential physiological role for bi-directional motility and motor clustering of mitotic kinesin-5 Cin8 in yeast mitosis

The bipolar kinesin-5 Cin8 switches from minus- to plus-end-directed motility under various conditions in vitro. The mechanism and physiological significance of this switch remain unknown. Here, we show that under high ionic strength conditions, Cin8 moves towards and concentrates in clusters at the...

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Detalles Bibliográficos
Publicado en:J Cell Sci
Main Authors: Shapira, Ofer, Goldstein, Alina, Al-Bassam, Jawdat, Gheber, Larisa
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339886/
https://ncbi.nlm.nih.gov/pubmed/28069834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.195040
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