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Evaluation of Adverse Drug Properties with Cryopreserved Human Hepatocytes and the Integrated Discrete Multiple Organ Co-culture (IdMOC(TM)) System

Human hepatocytes, with complete hepatic metabolizing enzymes, transporters and cofactors, represent the gold standard for in vitro evaluation of drug metabolism, drug-drug interactions, and hepatotoxicity. Successful cryopreservation of human hepatocytes enables this experimental system to be used...

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Detalhes bibliográficos
Publicado no:Toxicol Res
Autor principal: Li, Albert P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society Of Toxicology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505344/
https://ncbi.nlm.nih.gov/pubmed/26191380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2015.31.2.137
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