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In Vitro Antimalarial Activity of Different Inhibitors of the Plasmodial Isoprenoid Synthesis Pathway

Previous studies have shown that fosmidomycin, risedronate, and nerolidol exert antimalarial activity in vitro. We included squalestatin, an inhibitor of the isoprenoid metabolism in Erwinia uredovora, and found that combinations of compounds which act on different targets of the plasmodial isopreno...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: da Silva, Marcia F., Saito, Alexandre Y., Peres, Valnice J., Oliveira, Antonio C., Katzin, Alejandro M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505249/
https://ncbi.nlm.nih.gov/pubmed/26055383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04161-14
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