Evaluation of Ceftaroline Alone and in Combination against Biofilm-Producing Methicillin-Resistant Staphylococcus aureus with Reduced Susceptibility to Daptomycin and Vancomycin in an In Vitro Pharmacokinetic/Pharmacodynamic Model

Annually, medical device infections are associated with >250,000 catheter-associated bloodstream infections (CLABSI), with up to 25% mortality. Staphylococcus aureus, a primary pathogen in these infections, is capable of biofilm production, allowing organism persistence in harsh environments, off...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Barber, Katie E., Smith, Jordan R., Ireland, Cortney E., Boles, Blaise R., Rose, Warren E., Rybak, Michael J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505217/
https://ncbi.nlm.nih.gov/pubmed/25987623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00386-15
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