Pharmacodynamic Profile of GSK2140944 against Methicillin-Resistant Staphylococcus aureus in a Murine Lung Infection Model

GSK2140944 is a novel bacterial type II topoisomerase inhibitor with in vitro activity against key causative respiratory pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). We described the pharmacodynamics of GSK2140944 against MRSA in the neutropenic murine lung infection mode...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: So, Wonhee, Crandon, Jared L., Nicolau, David P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505212/
https://ncbi.nlm.nih.gov/pubmed/26055376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00625-15
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