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Characterization of Poliovirus Neutralization Escape Mutants of Single-Domain Antibody Fragments (VHHs)

To complete the eradication of poliovirus and to protect unvaccinated people subsequently, the development of one or more antiviral drugs will be necessary. A set of five single-domain antibody fragments (variable parts of the heavy chain of a heavy-chain antibody [VHHs]) with an in vitro neutralizi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Schotte, Lise, Thys, Bert, Strauss, Mike, Filman, David J., Rombaut, Bart, Hogle, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505203/
https://ncbi.nlm.nih.gov/pubmed/26014941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00878-15
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