Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) is an aggressive neoplasm with limited treatments for patients with advanced disease. The mucin 1 C-terminal subunit (MUC1-C) oncoprotein plays a critical role in regulating cell proliferation, apoptosis, and protection from cytotoxic injury mediated by reactive oxyg...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Jain, Salvia, Stroopinsky, Dina, Yin, Li, Rosenblatt, Jacalyn, Alam, Maroof, Bhargava, Parul, Clark, Rachael A., Kupper, Thomas S., Palmer, Kristen, Coll, Maxwell D., Rajabi, Hasan, Pyzer, Athalia, Bar-Natan, Michal, Luptakova, Katarina, Arnason, Jon, Joyce, Robin, Kufe, Donald, Avigan, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504948/
https://ncbi.nlm.nih.gov/pubmed/26048911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-628149
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