Mitochondrial transcription factor A regulation of mitochondrial degeneration in experimental diabetic neuropathy

Oxidative stress-induced mitochondrial dysfunction and mitochondrial DNA (mtDNA) damage in peripheral neurons is considered to be important in the development of diabetic neuropathy. Mitochondrial transcription factor A (TFAM) wraps mtDNA and promotes mtDNA replication and transcription. We studied...

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Опубликовано в: :Am J Physiol Endocrinol Metab
Главные авторы: Chandrasekaran, Krish, Anjaneyulu, Muragundla, Inoue, Tatsuya, Choi, Joungil, Sagi, Avinash Rao, Chen, Chen, Ide, Tamomi, Russell, James W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504935/
https://ncbi.nlm.nih.gov/pubmed/25944881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00620.2014
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