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TNFα induces inflammatory stress response in microvascular endothelial cells via Akt- and P38 MAP kinase-mediated thrombospondin-1 expression

Tumor necrosis factor-α (TNFα) and thrombospondin-1 (TSP-1) are well-known mediators of inflammation. However, a causal relationship between TNFα stimuli and TSP-1 expression in endothelial cell stress, and the underlying mechanisms has not yet been investigated. In our study, human microvascular en...

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Detalhes bibliográficos
Publicado no:Mol Cell Biochem
Main Authors: Fairaq, Arwa, Goc, Anna, Artham, Sandeep, Sabbineni, Harika, Somanath, Payaningal R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504829/
https://ncbi.nlm.nih.gov/pubmed/25963668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-015-2440-0
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