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Opiorphin-dependent up-regulation of CD73 (a key enzyme in the adenosine signaling pathway) in corporal smooth muscle cells exposed to hypoxic conditions and in corporal tissue in pre-priapic sickle cell mice

The precise molecular mechanisms underlying priapism associated with sickle cell disease remain to be defined. However, there is increasing evidence that up-regulated activity of the opiorphin and adenosine pathways in corporal tissue, resulting in heighted relaxation of smooth muscle, play an impor...

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Detalhes bibliográficos
Publicado no:Int J Impot Res
Main Authors: Fu, Shibo, Davies, Kelvin P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504813/
https://ncbi.nlm.nih.gov/pubmed/25833166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijir.2015.5
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