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The Role of Adenosine Signaling in Sickle Cell Therapeutics
Recent data suggest a role for adenosine signaling in the pathogenesis of sickle cell disease (SCD). Signaling through the adenosine A(2A) receptor (A(2A)R) has demonstrated beneficial effects in SCD. Activation of A(2A)Rs decreases inflammation in mice and patients with SCD largely by blocking acti...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3997263/ https://ncbi.nlm.nih.gov/pubmed/24589267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2013.11.003 |
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